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Innovative Patent

Joint Innovation: Peking University&SungenBio
Technology Patent(Sungenbio): ZL 03 1 09244.6
SungenBio Gains Pricing Power

High Activity

Multi-Stage Membrane Separation and Primary Column Chromatography for Product Refining
Specific Activity Up to 18000ATU/Mg

High Stability

Established the Quality Control Platform of Hirudin™
Heat Resistance (70°C), Acid and Alkali Resistance (Ph=3~9), Bile Resistance

Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches that is made up of 65 to 66 amino acids. It could inhibit the thrombin effectively and to be the most potent natural inhibitor of thrombin.

Currently, hirudin is divided into natural hirudin and recombinant hirudin.Recombinant hirudin respectively successfully expressed in E.coli and yeast. All were Thr2-63-desulfohirudin. Experiments show that recombinant hirudin provides the same stability, activity as a natural hirudin.

Specifications 18000ATU/mg 16000ATU/mg 12000ATU/mg

1. Blood Sample Tube Coating

Compared with traditional blood collection tubes, hirudin vacuum blood collection tubes are suitable for many types of detection items (blood routine, blood biochemistry, electrolytes, tumor markers, homocysteine and hepatitis B, etc.)with minimal dosage,which reduces the blood collection and medical costs of patients.

hirudin vacuum blood collection tubes(SungenBio)

2. Health food (additives)

As a supplement component of Chinese patent medicine, hirudin polypeptide can improve human microcirculation, eliminate free radicals, delay aging and reduce blood lipids. The effect of anti-coagulation and thrombolysis has also been proved by Clinical experiments

3. Medicine

Prevention and treatment of arteriovenous thrombosis diseases;Auxiliary treatment of acute myocardial infarction thrombolysis; Prevention of coronary occlusion.

4. Cosmetics (additives)

The molecular size of hirudin is between protein and peptide. It has strong permeability and can directly penetrate into the deep layer of skin directly, improve blood circulation and facial microcirculation, and promote skin rejuvenation. Hirudin has a unique effect on inhibiting or reducing the formation of melanin, whitening and sunscreen, as well as anti-inflammatory and anti-swelling,and may also be used to treat acne.


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